phenobarbital will reduce the extent or impact of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Potent or reasonable CYP3A4 inducers may well improve price of diazepam elimination; for that reason, efficacy of diazepam could be decreased.Utilization in Pregnancy. Barbiturates can cause fetal destru